Molecular Details
DICL_CP_0307281
- (2R)-2-amino-3-hydroxypropanoic acid
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0307281
PubChem CID
Molecular Formula
C3H7NO3 Molecular Weight
105.093 g/mol
Synonyms/Alias
[D-serine; 312-84-5; H-D-Ser-OH; (R)-2-amino-3-hydroxypropanoic acid; (R)-Serine; Serine D-form; (2R)-2-amino-3-hydroxypropanoic acid; Serine; D-; D-Serin; MFCD00004269; C3H7NO3; (2R)-2-amino-3-hydrox...
InChI Key
MTCFGRXMJLQNBG-UWTATZPHSA-N
InChI
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
IUPAC Name
(2R)-2-amino-3-hydroxypropanoic acid
CAS Number
2768959-22-2
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
14 13 0 0 0 0 0 0 0 0999 V2000
-1.2402 -0.6120 -0.0170 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.2898 0.5737 -0.2374 C 0 0 2 0 0 0 0 0 0 0 0 0
1.1333 0.106...
Experimental Data
Activity Data
Target Ion Channel
Glutamate receptor ionotropic subunit NMDA 1/2C
Uniprot Accession Number
Function
Agonist
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
EC50: 190 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−40 mV mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
GluN1 L654, V689, Y692, F753 and F754
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
7
Rotatable Bonds
2
logP
-1.6094
Complexity
22.697
TPSA (Ų)
83.55
H-Bond Donors
3
H-Bond Acceptors
3
Ring Count
0